prostaglandin-E synthase | |||||||
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Identifiers | |||||||
EC number | 5.3.99.3 | ||||||
CAS number | 52227-79-9 | ||||||
Databases | |||||||
IntEnz | IntEnz view | ||||||
BRENDA | BRENDA entry | ||||||
ExPASy | NiceZyme view | ||||||
KEGG | KEGG entry | ||||||
MetaCyc | metabolic pathway | ||||||
PRIAM | profile | ||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||
Gene Ontology | AmiGO / EGO | ||||||
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Prostaglandin E synthase (or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.[1][2]
The synthase generating PGE2 is a membrane-associated protein.
Humans express three prostaglandin-E synthase isozymes, each encoded by a separate gene:
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